Brann er en vanlig hendelse i showet. Den har dukket opp i over 100 episoder, inkludert:
* "The Telltale Head" (sesong 1, episode 1)
* "Bart Gets an F" (sesong 1, episode 2)
* "Homer's Odyssey" (sesong 1, episode 3)
* "There's No Disgrace Like Home" (sesong 1, episode 4)
* "Bart the Genius" (sesong 1, episode 6)
* "The Homer They Fall" (sesong 2, episode 1)
* "Bart blir truffet av en bil" (sesong 2, episode 3)
* "To biler i hver garasje og tre øyne på hver fisk" (sesong 2, episode 5)
* "Bart the Murderer" (sesong 3, episode 1)
* "Mr. Lisa Goes to Washington" (sesong 3, episode 2)
* "Black Widower" (sesong 3, episode 9)
* "Flaming Moe's" (sesong 3, episode 10)
* "Marge vs. the Monorail" (sesong 4, episode 12)
* "Mr. Plough" (sesong 4, episode 9)
* "Krusty Gets Busted" (sesong 4, episode 21)
* "Homer the Vigilante" (sesong 5, episode 1)
* "The Last Temptation of Homer" (sesong 5, episode 9)
* "Bart Gets Famous" (sesong 5, episode 12)
* "Cape Feare" (sesong 5, episode 2)
* "The Boy Who Knew Too Much" (sesong 5, episode 21)
* "The Springfield Files" (sesong 8, episode 10)
* "The Itchy &Scratchy &Poochie Show" (sesong 8, episode 14)
* "Homer's Enemy" (sesong 8, episode 23)
* "El Viaje Misterioso de Nuestro Jomer (The Mysterious Voyage of Our Homer)" (sesong 8, episode 9)
* "The Principal and the Pauper" (sesong 9, episode 1)
* "Lisa the Skeptic" (sesong 9, episode 8)
* "Bart Carny" (sesong 9, episode 12)
* "The Joy of Sect" (sesong 9, episode 13)
* "Das Bus" (sesong 9, episode 15)
* "The City of New York vs. Homer Simpson" (sesong 9, episode 1)
* "Thirty Minutes over Tokyo" (sesong 10, episode 19)
* "They Saved Lisa's Brain" (sesong 10, episode 22)
* "Maximum Homerdrive" (sesong 10, episode 15)
* "Viva Ned Flanders" (sesong 10, episode 18)
* "Bart to the Future" (sesong 11, episode 17)
* "Homers Barbershop Quartet" (sesong 11, episode 1)
* "The Mansion Family" (sesong 12, episode 9)
* "Hungry, Hungry Homer" (sesong 12, episode 15)
* "Sweets and Sour Marge" (sesong 12, episode 10)
* "Day of the Jackanapes" (s