- Newbery Honor Award for "Judy Moody and the Not Bummer Summer" (2011)
- Theodor Seuss Geisel Honor Award for "Stink and the Ultimate Showdown" (2009)
- California Young Reader Medal for "Judy Moody and the Not Bummer Summer" (2012)
- Rhode Island barnebokpris for "Judy Moody and the Not Bummer Summer" (2012)
- Georgia Children's Book Award for "Judy Moody and the Not Bummer Summer" (2013)
- Iowa Children's Choice Award for "Judy Moody and the Not Bummer Summer" (2013)
- Keystone State Reading Association Children's Book Award for "Judy Moody and the Not Bummer Summer" (2013)
I tillegg til disse har Megan McDonald også blitt anerkjent av American Library Association, Society of Children's Book Writers and Illustrators og National Education Association for sine bidrag til barnelitteratur.